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Disorder, Disease, and Health, part 1: Mapping the Space of Debate

I recently read Stein et al (2024), “Philosophy of psychiatry: Theoretical advances and clinical implications." This review article has the double merit of including some of the most prominent names in philosophy of psychiatry among its co-authors and of appearing in a psychiatry journal, World Psychiatry, thus promoting the relevance of philosophy to mental health professionals and researchers. As with any review article, breadth comes at the expense of depth, and, as with any review article, I find myself tempted to criticize it for its omissions rather than its inclusions. Yet despite its attempt to serve as a non-technical introduction to the subject, the paper deliberately advances several core positions in the debates it covers.

 

The authors select three thematic areas: 1) the nature of disorder; 2) pluralism in psychiatry (ontological, explanatory, axiological); and 3) enactivism or the “4E” framework as an integrative approach. I am going to focus here on the first of these. A review article cannot contribute a novel or even a nuanced answer to a philosophical question, but it can help map the space of debate in a useful way. That is what I think this article does.

 

Consider the following argument: the fundamental question of philosophy of medicine concerns the nature of disease and health. Insofar as philosophy of psychiatry is a branch of philosophy of medicine, these questions are also fundamental to it. Now, I am not sure the premises of this argument are true, but the argument is certainly deductively valid. Judging from scholarly output, it also seems to be popular. Indeed, Wilkinson’s textbook of philosophy of psychiatry, which I have had occasion before to treat as a barometer, starts with the question of what mental illness is and how it is to be differentiated from mental health. Flagging these sorts of questions as fundamental also brings philosophy of psychiatry into communion with standard non-specialist concerns—such as popular concerns about whether mental illness “really” is illness or whether specific conditions, such as alcoholism, should be treated as diseases or as moral failings.

 

Very roughly, the debate goes like this: some people think that what makes something a disease or disorder is purely an objective matter. Other people think that the question can only be answered by taking values into consideration. Stein et al call the first camp “naturalists” and the second camp “normativists.” Other writers use slightly different labels. Of course, the space of debate is actually much more complicated than this.

 

I admit, though, that I have a certain aversion to these questions as such. Having given the philosophical debate a cursory once-over, I have tended to think that the different parties are talking past each other—are answering different questions. I have also tended to think that much of the disagreement rests on the perceived implications of the different positions—especially the implications for questions about moral responsibility, public policy and allocation of scarce resources, or the conceptualization of specific conditions (again, think substance use disorders). But I would venture that the real action lies downstream. Figuring out what makes something a disease and what is and is not a disorder does not really solve, in my view, the question of where the boundaries of moral responsibility lie. So, in short, I have taken until now a rather deflationary attitude to the question of what health consists of or what makes something a disorder or a disease. My view up to now has been something like this: When we ask about how to define disease, disorder, and health—I am talking about real definition here, not nominal definitions—what we are really asking about is a whole bundle of other smaller questions that do not admit of any single global answer. There is no “wholesale” answer to these questions; we cannot avoid doing the real “retail” philosophical work to answer them (to borrow a metaphor from Brandom).

 

Stein et al convinced me to test these prejudices out. It would take me too long to say why, but in a nutshell I have come to think that the questions I have been exploring up to now about classification and the ontological status of diagnostic categories depend on more fundamental questions about what disorder and health consist of. In the coming weeks, I want to use the Stein et al bibliography to go through the debate in philosophy of medicine and philosophy of psychiatry about disease and health. This is a daunting task because the relevant literature—limiting myself just to the contemporary Anglophone debate growing out of Christopher Boorse’s work in the 1960s and 1970s—is so large. I will need a guide, so I will also use the Stein et al mapping of the debate, which they helpfully present in Table 1 (p. 217):

 

The table presents a menu of answers to four questions: 1) “Are there biological and behavioral states that can be characterized as dysfunctional or malfunctional in objective terms independent of human interests?”; 2) “Is there an essence that is shared by all dysfunctions?”; 3) “Is ‘dysfunction’ necessary for disorder status?”; and 4) “What are the relevant human interests [to judgments of disorder status]?”

 

There are a few things to note about this mapping. First, the concept of disorder usually takes precedence over disease in these discussions, and rightly so. Most of the relevant writers treat “disorder” as having a much wider extension than “disease,” so that all diseases would be disorders but not vice versa. I will honor this focus going forward while bearing in mind that “sick,” “disease,” and “ill” are much more common words in everyday discussions of these topics.

 

Second, the questions make it clear that the concept of dysfunction plays a central important role here. Many, but not all, of the positions in the table proceed from the premise that disorder involves dysfunction, which in turn raises questions about what makes a state of affairs dysfunctional—and whether we need to have a theory of functioning well to answer such questions. Thinking in terms of dysfunction is also deeply embedded in the DSM-5 introduction and in the ubiquitous “causes clinically significant distress or impairment” criterion appended to most sets of diagnostic criteria in the manual.

 

Finally, the question of relevant human interests indicates just how varied the normativist answer can turn out to be. In fact, I think the range of relevant concerns and interests is far broader than what is included here, and I wish the writers had paid attention to Quill Kukla’s recent work on the pragmatics of illness ascriptions. Perhaps I will move in that direction: from Boorse’s naturalism to Kukla’s pragmatism. I cannot promise, though, that I will stay on topic!

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